In vitro antifungal activity of ethanolic extract of Cocculus laurifolius leaves

02-HJPV1(1)-2019 Original Article

Abstract

The present study was designed to investigate the antifungal activity of ethanolic extract of Cocculus laurifolius leaves. The concentrations of 100, 200 and 400 µg/ml of ethanolic extract were used to evaluate the antifungal potential of extract. The experiment was conducted using agar disc diffusion method against five different fungal strains: Aspergillus niger, Micro sporumcanis, Candida glabrata, Trichphyton rubrum and Candida albicans. The antifungal activity was observed by estimating the zone of fungal growth inhibition. Cocculus laurifolius showed significant decrease in fungal growth at all selected concentrations. However, the extract revealed maximum zone of inhibition at higher doses. The outcomeof this study illustrated that ethanolic extract of Cocculus laurifolius leaves possess substantial in-vitro antifungal properties.