PHARMACOGNOSTIC AND PRELIMINARY PHYTOCHEMICAL STANDARDIZATION OF BARK EXTRACT OF SALACIA RETICULATA WIGHT.

19-HJPV3(1)-2022 Original Article

Authors

  • Hina Sharif Department of Pharmacognosy, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan.
  • Mahjabeen Department of Pharmacology, Faculty of Pharmacy, Federal Urdu University, Karachi, Pakistan.
  • Noor Jahan Department of Pharmacology, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.
  • Nudrat Fatima Department of Pharmacognosy, Faculty of Pharmacy, Jinnah University for Women Karachi, Pakistan.

DOI:

https://doi.org/10.61744/hjp.v2i1.27

Keywords:

Salacia reticulata, Celastraceae, Standardization, Phytochemical, Pharmacognostic

Abstract

Salacia reticulata Wight belongs to the family Celastraceae are renowned species of plant having hypoglycemic action. It is standardized based on preliminary phytochemical and pharmacognostic properties. Pharmacognostic studies have shown that S. reticulata dry bark has a yellowish outer surface while brown to dark brown color internally. It has a bitter taste with a characteristic odor. Under microscopic evaluation S. reticulata stem cross-section showed xylem, cambial zone with cells arranges in rows after the xylem, phloem driver, and other structures. Phytochemical standardization has revealed the presence of chemical components including Sterols, Tannins, Terpenoids, Saponins, Phenols, Flavonoids, and Carbohydrates, normal fluorescence behavior at normal, 254nm, and 366nm. In the TLC test two solvent systems, Chloroform-Methanol-Water (80:20:2) and Ethyl acetate-Methanol-Water (100:16.5:13.5) showed the presence of 11 chemical constituents that need to be further explored.

Author Biographies

Hina Sharif, Department of Pharmacognosy, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan.

Assistant professor,  Department of Pharmacognosy, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan.

Mahjabeen, Department of Pharmacology, Faculty of Pharmacy, Federal Urdu University, Karachi, Pakistan.

Assistant Professor, Department of Pharmacology, Faculty of Pharmacy, Federal Urdu University, Karachi, Pakistan.

Noor Jahan, Department of Pharmacology, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.

Professor, Department of Pharmacology, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.

Nudrat Fatima, Department of Pharmacognosy, Faculty of Pharmacy, Jinnah University for Women Karachi, Pakistan.

Professor, Department of Pharmacognosy, Faculty of Pharmacy, Jinnah University for Women Karachi, Pakistan.

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Published

2022-02-02

Issue

Vol. 2 No. 1 (2022): January - June Edition

Section

Full length Article